We havent gotten all of the mythics yet, but weve gotten a peek at Battles
Players can lose the game by losing all of their cards or life, but taking 21 damage from the Commander also counts as a loss
Niche cases, sure, but they will happen
Beyond this the synergies are subtle and tend to only involve a few cards, for example Chandra's Phoenix improves Lava Dart, the few creature pump effects improve Spikeshot Elder, Mogg Fanatic and other creature sacrifice effects improve Brimstone Volley and the things that give haste work really well with Keldon Marauders
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