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Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 Zimmermann

SKU: 30675879671

4.4
USD495.00 USD520.00

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Description

Zimmermann

a synthetic antibiotic

653 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

thus has excellent cell permeability

HaloTag is a self-labeling protein derived from the haloalkane dehalogenase DhaA from Rhodococcus rhodochrous

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE mal-propionyl-dap-m-PEG4 ZimmermannSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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