Thalidomide-O-acetamido-C1-acid tamra 381 SMILES OC(=O)CCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)

381 SMILES OC(=O)CCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

also referred to as the Cu(I)-catalyzed free click reaction

The water soluble 5(6)-TAMRA PEG3 azide has a long PEG3 spacer that separates the dye tetramethylrhodamine (commonly known as TMR or TAMRA) from the terminal azide group

677 SMILES: [O-]C(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)C(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

The conjugate has better solubility than the parent dye carboxyrhodamine and its long PEG spacer should reduce any steric effect of the dye on the molecule to be labelled

Thalidomide-O-acetamido-C1-acid tamra 381 SMILES OC(=O)CCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)Degrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Thalidomide O acetamido C1 acid Synonyms Thalidomide 4' O acetamido C1 acid CAS Number n a Related CAS Molecular Formula C17H15N3O8 Molecular Weight 389. 32 SMILES OC(=O)CNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1