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Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C88H139N15O24 Molecular Weight 1791
64 SMILES Cl
Product Name 2-chloro-5-(methoxy-d3)pyrimidine Synonyms CAS Number n/a Related CAS Molecular Formula C5H5ClN2O Molecular Weight 147
N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C9H12ClN Molecular Weight 175
Fitzgibbons
Propargyl-Acetyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE deuterium-labeled-amine Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
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