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Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP m-peg8-pab Cell Reports 2021

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Description

Cell Reports 2021

A Study Evaluating the Efficacy and Safety of Inavolisib + Palbociclib + Fulvestrant vs Placebo + Palbociclib + Fulvestrant in Patients With PIK3CA-Mutant

489 SMILES OCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Pomalidomide-CO-C5-azide Synonyms Pomalidomide-4'-CO-C5-azide CAS Number 2227423-33-6 Related CAS Molecular Formula C19H20N6O5 Molecular Weight 412

DOTA bifucational chelator containing a carboxylic acid group

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP m-peg8-pab Cell Reports 2021SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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